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Publications

Peer-reviewed Journal Articles

[28] Ekpenyong AE, N Toepfner, et al. (2017) Mechanical deformation induces depolarization of neutrophils. Science Advances  Vol 3, No. 6. 10.1126/sciadv.1602536

[27] SV Prathivadhi-Bhayankaram, J Ning, M Mimlitz, C Taylor, E Gross, ...A. Ekpenyong. (2016) Chemotherapy impedes in vitro microcirculation and promotes migration of leukemic cells with impact on metastasis. Biochemical and Biophysical Research Communications 479 (4), 841-846.

[26] Ekpenyong AE, N Toepfner, ER Chilvers, J Guck. (2015) Mechanotransduction
in neutrophil activation and deactivation Biochimica et Biophysica Acta (BBA) 1853 (11):3105-3116. doi:10.1016/j.bbamcr.2015.07.015.

[25] Chan CJ,Ekpenyong AE*, Golfier S, Li W, Chalut KJ, et al. (2015)
Myosin II activity softens cells in suspension. Biophys J.
doi:10.1016/j.bpj.2015.03.009. (Where * indicates co-first author).

[24] Otto O, Rosendahl P, Mietke A, Golfier S, Herold C, Klaue D, Girardo
S, Pagliara S, Ekpenyong A, et al. (2015) Real-time deformability cytometry: on-the-fly cell mechanical phenotyping. Nat Methods 12(3):199-202. doi:10.1038/nmeth.3281

[23] Man SM, Ekpenyong AE*, Tourlomousis T, Achouri S, Cammarota E,
et al. (2014) Actin polymerization as a novel innate immune effector
mechanism to control Salmonella infection. Proc Natl Acad Sci USA
doi:10.1073/pnas.1419925111.

[22] Holmes D, Whyte G, Bailey J, Vergara-Irigaray N, Ekpenyong AE, et
al. (2014) Separation of blood cells with differing deformability using
deterministic lateral displacement. Interface Focus 4:6, 20140011

[21] Ekpenyong AE, Man SM, Achouri S, Bryant C, Guck J, et al. (2013)
Bacterial infection of macrophages induces decrease in refractive index.
J Biophotonics 6:5, 393-397. doi:10.1002/jbio.201200113

[20] Boyde L, Ekpenyong A, Whyte G, Guck J (2013) Elastic Theory for
the Deformation of a Solid or Layered Spheroid under AxisymmetricLoading. Acta Mechanica 224: 4, 819-839

[19] Ekpenyong AE, Whyte G, Chalut K, Pagliara S, Lautenschlæger F, et
al. (2012) Viscoelastic Properties of Differentiating Blood Cells Are
Fate- and Function-Dependent. PLoS ONE 7: e45237. doi:10.1371/journal.pone.0045237

[18] Chalut KJ, Ekpenyong AE*, Clegg WL, Melhuish IC, Guck J (2012)
Quantifying cellular differentiation by physical phenotype using digital
holographic microscopy. Integr Biol (Camb) 4: 280−284. doi:10.1039/c2ib00129b

[17] Boyde L, Ekpenyong A, Whyte G, Guck J (2012) Comparison of
stresses on homogeneous spheroids in the optical stretcher computed
with geometrical optics and generalized Lorenz-Mie theory. Appl Opt 51: 33, 7934-7944

[16] Ekpenyong AE, Posey CL, Chaput JL, Burkart AK, Marquardt MM,
et al. (2009) Determination of cell elasticity through hybrid ray optics
and continuum mechanics modeling of cell deformation in the optical
stretcher. Appl Opt 48: 6344−6354. doi:10.1364/AO.48.006344

[15] Jacobs KM, Yang L V., Ding J, Ekpenyong AE, Castellone R, et
al. (2009) Diffraction imaging of spheres and melanoma cells with a
microscope objective. J Biophotonics 2: 521−527.
doi:10.1002/jbio.200910044
 

Conference Publications

[14] Ekpenyong A, Guck J (2014) The Evolution of Mechanical Properties
of Differentiating Stem Cells is Fate-and Function-Dependent. Biophysical J 106: 2, 42a

[13] Ekpenyong AE, Chalut K, Whyte G, Guck J. (2011) Optical stretching
and digital holography quantify physical phenotypes of differentiating
cells. Institute of Physics, Quantitative Methods in Gene Regulation,London.

[12] Whyte G, Lautenschlæger F, Kreysing M, Boyde L, Ekpenyong A, Delabre
U, et al. (2010) Dual-beam laser traps in biology and medicine: when one beam is not enough SPIE NanoScience and Engineering,77620G-77620G-6.

[11] Jacobs KM, Ding J, Yang LV, Reynolds CL, Ekpenyong AE, Feng Y et
al. (2010) Diffraction Imaging Flow Cytometric and 3-D Morphological Analysis of Three Cell Lines. Biomedical Optics, OSA Technical Digest (CD) paper BTuD44

[10] Ekpenyong AE, Ding J, Yang L V., Leffler NR, Lu JQ, et al. (2009)
Study of 3D cell morphology and effect on light scattering distribution.
Proceedings of SPIE 7367: 73671J-7. doi:10.1117/12.831510

[9] Ekpenyong, AE, and MG Nichols. (2007) Hybrid Ray Optics and
Continuum Mechanics Modeling of Cell Deformation in the Optical
Stretcher. in Frontiers in Optics 2007/Laser Science XXIII/Organic
Materials and Devices for Displays and Energy Conversion. Optical
Society of America
, Washington, DC.JWC11.

[8] Ekpenyong, Andrew E, (2004) World Year of Physics 2005 and the
Planetary Emergencies in Proceedings of the 45th Annual Conference
of the Science Teachers’ Association of Nigeria
, ed. Matthias Akale,
Heinemann Books, Ibadan, Nigeria. Paper 37, pages 192-196.
 

Invited Talks, (International Conferences)

[7] Ekpenyong, AE, Schuermann, M, Man, SM, Achouri, S, Guck, J, et al.
Monitoring cell differentiation and infection using Digital Holographic
Microscopy. European Conferences on Biomedical Optics (ECBO). 12
May, 2013, Munich, Germany.

[6] Ekpenyong, AE, Guck, JR, et al. Viscoelastic properties of differentiating
cells evolve to meet tissue-specific functions. Dynamics of Tissues
and Multicellular Systems
. 14 Dec 2012, Leipzig, Germany.

Contributed Talks (International Conferences)

[5] Ekpenyong, AE, Whyte, GB, Chalut, KJ, Pagliara, S, Guck, JR, et
al. Contributions of actin and myosin to creep compliance of blood
stem cells during differentiation. Optical Trapping and Optical Micromanipulation
X, SPIE NanoScience and Engineering. 28 Aug 2013,San Diego, USA.

[4] Ekpenyong, AE, Whyte, GB, Lautenschlaeger, F, Guck, JR, et al.Viscoelastic
properties of differentiating blood stem cells evolve to suit their functions.
Spring Meeting of the German Physical Society (DPG). 15
March 2013, Regensburg, Germany.

[3] Ekpenyong, AE,Whyte, GB, Chilvers, ER, Guck, JR, et al. Fate- and
function-dependent evolution of cellular mechanical properties during
myeloid haematopoiesis. 4th International Congress on Stem Cells
and Tissue Formation.
20 July 2012, Dresden, Germany.

Some Books

[2] Ekpenyong AE (2007) Basics of Physics for Senior Secondary Schools
3 Vols, Spectrum Books, Ibadan, Nigeria. 777 pages.

[1] Ekpenyong AE (2005) On the Many Faces of AIDS: Biblical, Medical,
and Moral Perspectives on HIV/AIDS. Temavic, Calabar, Nigeria.

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